Immunotherapy for advanced melanoma.

  title={Immunotherapy for advanced melanoma.},
  author={Lei Fang and A S Lonsdorf and Sam Hwang},
  journal={The Journal of investigative dermatology},
  volume={128 11},
Immunotherapy for melanoma has undergone significant change since the first attempts to treat patients with high dose IL-2. Herein, strategies to boost patient antitumor immunity through vaccination, treatment with agents that augment host immunity, and adoptive cell transfer will be discussed. The first two strategies have yielded only limited clinical success, but adoptive cell transfer therapy, particularly following a lymphodepleting, preconditioning regimen has resulted in objective… CONTINUE READING