Immunotherapy for Alzheimer's disease.

  title={Immunotherapy for Alzheimer's disease.},
  author={Richard C. Dodel and Harald Hampel and Yansheng Du},
  journal={The Lancet. Neurology},
  volume={2 4},
Recent studies in murine models of Alzheimer's disease (AD) have found that active immunisation with amyloid-beta peptide (Abeta) or passive immunisation with Abeta antibodies can lessen the severity of Abeta-induced neuritic plaque pathology through the activation of microglia. These antibodies can be detected in the serum and CSF. Whether they slow down or speed up the development and progression of AD has not been determined. Furthermore, the conditions that induce formation of such… CONTINUE READING

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