Immunotherapy for Acne Vulgaris: Current Status and Future Directions

  title={Immunotherapy for Acne Vulgaris: Current Status and Future Directions},
  author={T. Simonart},
  journal={American Journal of Clinical Dermatology},
  • T. Simonart
  • Published 2013
  • Medicine
  • American Journal of Clinical Dermatology
There is a high unmet clinical need for new and better treatments in acne vulgaris. Propionibacterium acnes has a strong proinflammatory activity and targets molecules involved in the innate cutaneous immunity, keratinocytes and sebaceous glands of the pilosebaceous follicle. The role of P. acnes in acne confers legitimacy on the possible benefits of immunization-based approaches, which may represent a solution for limiting the development of antibiotic-resistant P. acnes. Various immunization… Expand
9 Citations
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