Immunotherapy – 2068. Immunomodulatory and safety profile of a novel anti-allergic vaccine based on allergens from dermatophagoides siboney and a combination adjuvant, in sensitized mice


Background Th1/Tr1 promoting adjuvants, in allergen-specific vaccines, could be a valuable alternative to the current allergen immunotherapy. It is now the pro-Th1 adjuvant effect of Neisseria meningitidis proteoliposome (PL). Previous studies in a prophylactic murine model of respiratory allergy the vaccine showed its immunogenicity and safety. To assess… (More)


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