Immunotherapy: past, present and future

@article{Waldmann2003ImmunotherapyPP,
  title={Immunotherapy: past, present and future},
  author={Thomas A. Waldmann},
  journal={Nature Medicine},
  year={2003},
  volume={9},
  pages={269-277}
}
  • T. Waldmann
  • Published 1 March 2003
  • Biology, Medicine
  • Nature Medicine
Harnessing the immune system to treat chronic infectious diseases or cancer is a major goal of immunotherapy. Among others, impediments to this aim include host failure to identify tumor antigens, tolerance to self and negative immunoregulatory mechanisms. But with recent progress, active and passive immunotherapy are proving themselves as effective therapeutic strategies. 

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Immunologic memory, or the ability to respond more rapidly and effectively to the previously encountered pathogens, represents a fundamental feature of the adaptive immune system. Such memory

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Some medical implications of DC biology that account for illness and provide opportunities for prevention and therapy are presented.
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