Immunotherapy: past, present and future

@article{Waldmann2003ImmunotherapyPP,
  title={Immunotherapy: past, present and future},
  author={T. Waldmann},
  journal={Nature Medicine},
  year={2003},
  volume={9},
  pages={269-277}
}
  • T. Waldmann
  • Published 2003
  • Medicine
  • Nature Medicine
  • Harnessing the immune system to treat chronic infectious diseases or cancer is a major goal of immunotherapy. Among others, impediments to this aim include host failure to identify tumor antigens, tolerance to self and negative immunoregulatory mechanisms. But with recent progress, active and passive immunotherapy are proving themselves as effective therapeutic strategies. 
    542 Citations

    Figures and Topics from this paper

    Explore Further: Topics Discussed in This Paper

    Progress on new vaccine strategies for the immunotherapy and prevention of cancer.
    • 255
    • PDF
    Immunotherapy in acute leukemia.
    • W. Leung
    • Medicine
    • Seminars in hematology
    • 2009
    • 5
    Frontiers in nephrology: T cell memory as a barrier to transplant tolerance.
    • 76
    • PDF
    Vaccines and Immunotherapeutics for the Treatment of Malignant Disease
    • 35
    • PDF
    Immunotherapy as an Option for Cancer Treatment
    • 12
    Cytokine, chemokine, and co-stimulatory fusion proteins for the immunotherapy of solid tumors.
    • 34
    Effective cancer therapy through immunomodulation.
    • T. Waldmann
    • Biology, Medicine
    • Annual review of medicine
    • 2006
    • 98

    References

    SHOWING 1-10 OF 93 REFERENCES
    Vaccines: Spinning molecular immunology into successful immunotherapy
    • D. Pardoll
    • Biology, Medicine
    • Nature Reviews Immunology
    • 2002
    • 365
    The prime-boost strategy: exciting prospects for improved vaccination.
    • 367
    Immunotherapy of human cancer: lessons from mice
    • 151
    • PDF
    Improving the efficacy of antibody-based cancer therapies
    • 804
    • PDF
    Tumor antigens recognized by T cells.
    • 573
    Strategies for designing and optimizing new generation vaccines
    • 351
    • PDF
    Human tumor antigens recognized by T cells.
    • 228
    [Monoclonal antibodies in diagnosis and therapy].
    • 54
    Therapeutic antibodies: Magic bullets hit the target
    • 135