Immunotherapeutic strategies to prevent and treat human herpesvirus 6 reactivation after allogeneic stem cell transplantation.

@article{Gerdemann2013ImmunotherapeuticST,
  title={Immunotherapeutic strategies to prevent and treat human herpesvirus 6 reactivation after allogeneic stem cell transplantation.},
  author={Ulrike Gerdemann and Laura Keukens and Jacqueline M Keirnan and Usha L. Katari and Chinh Tran Nguyen and Anne P. J. de Pagter and Carlos A Ramos and Alana A. Kennedy-Nasser and Stephen Gottschalk and Helen E Heslop and Malcolm K. Brenner and Cliona M Rooney and Ann M. Leen},
  journal={Blood},
  year={2013},
  volume={121 1},
  pages={207-18}
}
Human herpesvirus (HHV) 6 causes substantial morbidity and mortality in the immunocompromised host and has no approved therapy. Adoptive transfer of virus specific T cells has proven safe and apparently effective as prophylaxis and treatment of other virus infections in immunocompromised patients; however, extension to subjects with HHV6 has been hindered by the paucity of information on targets of cellular immunity. We now characterize the cellular immune response from 20 donors against 5… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 52 references

Early human herpesvirus type 6 reactivation after allogeneic stem cell transplantation: a large-scale clinical study.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation • 2012

Different characteristics of human herpesvirus 6 encephalitis between primary infection and viral reactivation.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology • 2011

Human herpesvirus 6 infection after hematopoietic cell transplantation: is routine surveillance necessary?

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation • 2011

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