Immunosuppressive total lymphoid irradiation-based reconditioning regimens enable engraftment after graft rejection or graft failure in patients treated with allogeneic hematopoietic stem cell transplantation.

@article{Heinzelmann2008ImmunosuppressiveTL,
  title={Immunosuppressive total lymphoid irradiation-based reconditioning regimens enable engraftment after graft rejection or graft failure in patients treated with allogeneic hematopoietic stem cell transplantation.},
  author={Frank Heinzelmann and Peter J. Lang and Hellmut Ottinger and Christoph Faul and Wolfgang Andreas Bethge and Rupert Handgretinger and Michael Bamberg and Claus Belka},
  journal={International journal of radiation oncology, biology, physics},
  year={2008},
  volume={70 2},
  pages={523-8}
}
PURPOSE To retrospectively evaluate the efficacy of total lymphoid irradiation (TLI)-based reconditioning regimens in patients with graft failure or graft rejection after allogeneic hematopoietic stem cell transplantation. METHODS AND MATERIALS The results of 14 patients (7 adults and 7 children) with a variety of hematologic malignant diseases treated with a TLI-based reconditioning regimen with 7-Gy single-dose application plus anti-T-lymphocyte antibody OKT3 (n = 11) and/or antithymocyte… CONTINUE READING

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