Immunosuppressive therapy for active lymphocytic myocarditis: virological and immunologic profile of responders versus nonresponders.

@article{Frustaci2003ImmunosuppressiveTF,
  title={Immunosuppressive therapy for active lymphocytic myocarditis: virological and immunologic profile of responders versus nonresponders.},
  author={Andrea Frustaci and Cristina Chimenti and Fiorella Calabrese and Maurizio Pieroni and Gaetano Thiene and A. Lacasa Maseri},
  journal={Circulation},
  year={2003},
  volume={107 6},
  pages={
          857-63
        }
}
BACKGROUND The beneficial effect of immunosuppressive treatment on myocarditis is still controversial, possibly because the immunologic and virological profile of potential candidates is largely unknown. METHODS AND RESULTS Out of 652 biopsied patients, 112 had a histological diagnosis of active lymphocytic myocarditis; 41 of these 112 patients were characterized by progressive heart failure despite conventional therapy and were treated with prednisone and azathioprine for 6 months. All were… CONTINUE READING

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