Immunosuppressive property of bromocriptine on human B lymphocyte function in vitro

  title={Immunosuppressive property of bromocriptine on human B lymphocyte function in vitro},
  author={K. Morkawa and F. Oseko and S. Morikawa},
  journal={Clinical & Experimental Immunology},
  • K. Morkawa, F. Oseko, S. Morikawa
  • Published 1993
  • Biology, Medicine
  • Clinical & Experimental Immunology
  • Bromocriptine (BRC), a dopamine ergot alkaloid, inhibits the release of pituitary prolactin (PRL). Hypoprolactinaemia induced in rat by treatment with BRC produces a similar immunosuppressive effect as observed in hypophysectomized rats. The effect of immunosuppression by the administration of BRC has been interpreted as the result of hypoprolactinaemia produced by BRC. However, the direct effect of BRC on lymphocyte function has never been evaluated. The purpose of this study was to… CONTINUE READING
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