Immunosuppressive effect of cyclosporin A on insect humoral immune response.

  title={Immunosuppressive effect of cyclosporin A on insect humoral immune response.},
  author={Marta J Fiolka},
  journal={Journal of invertebrate pathology},
  volume={98 3},
Cyclosporin A suppressed humoral immune response of Galleria mellonella larvae. Insects were immunized with LPS Pseudomonas aeruginosa and then injected with cyclosporin A. Immunosuppressive effects were expressed both, in larvae treated with cyclosporin A at the initial phase of immune response and at the effector phase of antibacterial immunity. Cyclosporin A moderately decreased lysozyme activity and significantly decreased antibacterial activity peptides against Escherichia coli… CONTINUE READING

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