Immunosuppressive and other Effects of Mycophenolic Acid and an Ester Prodrug, Mycophenolate Mofetil

@article{Allison1993ImmunosuppressiveAO,
  title={Immunosuppressive and other Effects of Mycophenolic Acid and an Ester Prodrug, Mycophenolate Mofetil},
  author={A. Allison and E. Eugui},
  journal={Immunological Reviews},
  year={1993},
  volume={136}
}
The advantages and limitations of currently used immunosuppressive drugs are well known. Each drug has specific side effects: for example, cyclophosphamide can produce hemorrhagic cystitis (Levine & Jarrad 1993); cyclosporin can cause nephrotoxicity and hypertension (Bennett & Pulliam 1983); and methotrexate may lead to liver damage, pneumonitis and bone marrow suppression (Jolivet et al. 1983). In addition, there are short-term and long-term effects common to many immunosuppressive drugs. In… Expand
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