Immunosuppressive and autoimmune effects of thimerosal in mice.

  title={Immunosuppressive and autoimmune effects of thimerosal in mice.},
  author={Said Havarinasab and Bo H{\"a}ggqvist and Erik Bj{\"o}rn and Kenneth Michael Pollard and Per Hultman},
  journal={Toxicology and applied pharmacology},
  volume={204 2},
The possible health effects of the organic mercury compound thimerosal (ethylmercurithiosalicylate), which is rapidly metabolized to ethylmercury (EtHg), have recently been much debated and the effect of this compound on the immune system is largely unknown. We therefore studied the effect of thimerosal by treating A.SW (H-2s) mice, susceptible to induction of autoimmunity by heavy metals, with 10 mg thimerosal/L drinking water (internal dose ca 590 microg Hg/kg body weight/day) for up to 30… CONTINUE READING