Immunosuppressive and anti-inflammatory properties of interleukin 10.

  title={Immunosuppressive and anti-inflammatory properties of interleukin 10.},
  author={Jan de Vries},
  journal={Annals of medicine},
  volume={27 5},
Interleukin 10 (IL-10) indirectly prevents antigen-specific T-cell activation, which is associated with downregulation of the antigen presentation and accessory cell functions of monocytes, macrophages, Langerhans cells and dendritic cells. In addition, IL-10 inhibits T-cell expansion by directly inhibiting IL-2 production by these cells. These properties of IL-10, together with its capacity to downregulate the production of proinflammatory cytokines and chemokines by activated monocytes… CONTINUE READING
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