Immunosuppressive activity of CD14+ HLA‐DR− cells in squamous cell carcinoma of the head and neck

@article{Chikamatsu2012ImmunosuppressiveAO,
  title={Immunosuppressive activity of CD14+ HLA‐DR− cells in squamous cell carcinoma of the head and neck},
  author={K. Chikamatsu and K. Sakakura and M. Toyoda and Katsumasa Takahashi and Takanori Yamamoto and K. Masuyama},
  journal={Cancer Science},
  year={2012},
  volume={103}
}
Myeloid‐derived suppressor cells (MDSC) represent a heterogeneous population and have the potential to suppress immune responses via diverse mechanisms. In recent studies, a new subset of MDSC was identified by the markers CD14+ and HLA‐DR− in the peripheral blood from cancer patients. In this study, we investigated the proportions and characteristics of CD14+ HLA‐DR− cells in patients with squamous cell carcinoma of the head and neck (SCCHN). As expected, the percentage of CD14+ HLA‐DR− cells… Expand
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