Immunosuppressive Tumor Microenvironment Status and Histological Grading of Endometrial Carcinoma

@article{Antomarchi2019ImmunosuppressiveTM,
  title={Immunosuppressive Tumor Microenvironment Status and Histological Grading of Endometrial Carcinoma},
  author={Julie Antomarchi and Damien Ambrosetti and Charlotte Cohen and J. Delotte and Anne Chevallier and Babou Karimdjee-Soilihi and M{\'e}lanie Ngo-Mai and Annie Schmid-Alliana and Heidy Schmid-Antomarchi},
  journal={Cancer Microenvironment},
  year={2019},
  pages={1-11}
}
The recent successes of new cancer immunotherapy approaches have led to investigate their relevance in the context of the Endometrial Carcinoma (EC). These therapies, that take the tumor-induced immunosuppressive microenvironment into account, target the tumor immune escape, in particular the inhibitory receptors involved in the regulation of the effector T cells’ activity (immune checkpoints). The aim of this study was to identify, in ECs, differences in intergrades immune status that could… CONTINUE READING

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