Immunosuppression with mTOR inhibitors prevents the development of donor-specific antibodies after liver transplant.

@article{Willuweit2017ImmunosuppressionWM,
  title={Immunosuppression with mTOR inhibitors prevents the development of donor-specific antibodies after liver transplant.},
  author={Katharina Willuweit and Andreas Heinold and Jassin Rashidi-Alavijeh and Falko Markus Heinemann and Peter A. Horn and Andreas Paul and Guido G H Gerken and Kerstin Herzer},
  journal={Clinical transplantation},
  year={2017},
  volume={31 6}
}
BACKGROUND Donor-specific antibodies (DSAs) are an important cause of complications after solid organ transplant. Risk factors and, thus, strategies for preventing DSA development are not well defined. METHODS The DSA status of 400 patients who underwent liver transplant (LT) at the outpatient clinic of the University Hospital Essen was determined. Human leukocyte antigen (HLA) antibodies were detected by single-antigen bead technology. The strength of DSAs was reported as mean fluorescence… CONTINUE READING
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References

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SHOWING 1-10 OF 25 REFERENCES

De novo donor-specific HLA antibodies decrease patient and graft survival in liver transplant recipients.

  • American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
  • 2013
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

De novo donor-specific anti-HLA antibodies mediated rejection in liver-transplant patients.

  • Transplant international : official journal of the European Society for Organ Transplantation
  • 2015
VIEW 1 EXCERPT

Antibody-mediated rejection as a contributor to previously unexplained early liver allograft loss.

  • Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
  • 2014
VIEW 2 EXCERPTS

Prevalence, incidence and risk factors for donor-specific anti-HLA antibodies in maintenance liver transplant patients.

  • American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
  • 2014
VIEW 2 EXCERPTS

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