Immunosuppression of aquatic organisms exposed to elevated levels of manganese: From global to molecular perspective.

  title={Immunosuppression of aquatic organisms exposed to elevated levels of manganese: From global to molecular perspective.},
  author={Bodil E Hernroth and Helena Tassidis and Susanne Pihl Baden},
  journal={Developmental and comparative immunology},
6 Citations
Sirt3-Sod2-mROS-Mediated Manganese Triggered Hepatic Mitochondrial Dysfunction and Lipotoxicity in a Freshwater Teleost.
For the first time, it is demonstrated that Mn-induced hepatic lipotoxicity via a mitochondrial oxidative stress-dependent Hsf1/Pparg pathway and Mtf1/sirt3-mediated Sod2 acetylation participated in mitochondrial dysfunction.
NanoSIMS Imaging of Bioaccumulation and Subcellular Distribution of Manganese During Oyster Gametogenesis.
Great differences of the subcellular localization and accumulation capacity of Mn between oocytes and sperm cells in oysters are demonstrated, implying the sex differentiation in susceptibility of reproductive response to Mn stress.
Environmental Aspects of Historical Ferromanganese Tailings in the Šibenik Bay, Croatia
The former manganese ferroalloy plant and the remaining tailings are affecting the quality of the environment in Šibenik Bay, Croatia, even though industrial activities ceased more than 25 years ago.
Experimental evaluation of survival of Vibrio parahaemolyticus in fertilized cold‐water sediment
This experimental study focuses on survival and consistence of Vibrio parahaemolyticus in cold‐water sediments and how increasing temperature and nutritional availability can affect growth.


Transcriptional and Biochemical Effects of Cadmium and Manganese on the Defense System of Octopus vulgaris Paralarvae
Paralarvae exposed to high concentrations of cadmium and manganese exerted a concentration-dependent inhibition of survival and a reduction in growth rate was shown while Mn exposure did not affect the survival rate even at the highest concentrations.
Manganese exposure, essentiality & toxicity.
Exposure to high oral, parenteral, or ambient air concentrations of Mn can result in elevations in Mn tissue levels and neurological effects, and physiologically based pharmacokinetic models are being developed to provide for the ability to conduct route-to-route extrapolations, evaluate nasal uptake to the CNS, and evaluate lifestage differences in Mn pharmacokinetics.
Role, routes and effects of manganese in crustaceans
Results show that the immune system, the perception of food via chemosensory organs and a normal muscle extension are affected at manganese concentrations observed in the field, which is an unforeseen toxic metal in the aquatic environment.