Immunosuppression induced by acute exposure to cocaine is dependent on metabolism by cytochrome P-450.

Abstract

The primary objective of this paper was to characterize the role of metabolism in immunosuppression by acute exposure to cocaine. beta-Ionone has been used to study the role of metabolism in hepatotoxicity associated with acute exposure to cocaine, and was shown to produce a greater effect than other cytochrome P-450 (P-450) inducers. When beta-ionone (600… (More)

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Cite this paper

@article{Jeong1996ImmunosuppressionIB, title={Immunosuppression induced by acute exposure to cocaine is dependent on metabolism by cytochrome P-450.}, author={T. C. Jeong and Scott Jordan and Ray A. Matulka and Eric Stanulis and S. S. Park and Mathew Holsapple}, journal={The Journal of pharmacology and experimental therapeutics}, year={1996}, volume={276 3}, pages={1257-65} }