Immunosuppression in melanoma immunotherapy: potential opportunities for intervention.


Although melanomas are substantially more immunogenic than other tumors, current immunotherapeutic approaches for melanoma patients have met with only limited success. Although melanoma-specific CD8+ T-cell responses can often be generated in patients naturally or through vaccination regimens, tumors frequently continue to grow unabated, suggesting that… (More)


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@article{Lizee2006ImmunosuppressionIM, title={Immunosuppression in melanoma immunotherapy: potential opportunities for intervention.}, author={Gregory A. Lizee and Laszlo G. Radvanyi and Willem W. Overwijk and Patrick Hwu}, journal={Clinical cancer research : an official journal of the American Association for Cancer Research}, year={2006}, volume={12 7 Pt 2}, pages={2359s-2365s} }