Immunosuppression in aplastic anemia--postponing the inevitable?

@article{Moore1991ImmunosuppressionIA,
  title={Immunosuppression in aplastic anemia--postponing the inevitable?},
  author={Malcolm A. S. Moore and Hugo Castro-Malaspina},
  journal={The New England journal of medicine},
  year={1991},
  volume={324 19},
  pages={
          1358-60
        }
}
Mathe et al. reported in 1970 that when some patients with aplastic anemia received an allogeneic marrow transplant together with a conditioning immunosuppressive regimen of antilymphocyte globulin, they recovered autologous hematopoietic function.1 Subsequent trials of antilymphocyte globulin or antithymocyte globulin, alone or with steroids, resulted in hematologic improvement in 40 to 80 percent of patients with severe aplastic anemia. This effect was matched by improvement in one-year… CONTINUE READING
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