Immunostimulatory bioactivity of algal polysaccharides from Chlorella pyrenoidosa activates macrophages via Toll-like receptor 4.

@article{Hsu2010ImmunostimulatoryBO,
  title={Immunostimulatory bioactivity of algal polysaccharides from Chlorella pyrenoidosa activates macrophages via Toll-like receptor 4.},
  author={Hsien-Yeh Hsu and Narumon Jeyashoke and Chin-Hsi Yeh and Yuan-Jaw Song and Kuo-Feng Hua and Louis Kuoping Chao},
  journal={Journal of agricultural and food chemistry},
  year={2010},
  volume={58 2},
  pages={927-36}
}
Much research suggests that a dietary supplement of Chlorella pyrenoidosa may be helpful to human health, but the molecular mechanism involved remains unclear. The aim of this research was to investigate the effects of certain hot-water-soluble polysaccharides from Chlorella pyrenoidosa (CWSP) on cytokine production, human leukocyte antigen (HLA) expression, and costimulatory molecule expression in macrophages. We demonstrated that CWSP induced IL-1beta secretion in macrophages via Toll-like… CONTINUE READING
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