Immunostimulation by bacterial components: II. Efficacy studies and meta-analysis of the bacterial extract OM-89.

@article{Huber2000ImmunostimulationBB,
  title={Immunostimulation by bacterial components: II. Efficacy studies and meta-analysis of the bacterial extract OM-89.},
  author={M. C. E. Huber and K. E. Krauter and Georg Winkelmann and Hartwig Wilhelm Bauer and Volker W. Rahlfs and Pierre A Lauener and G. Blessmann and Wolfgang Bessler},
  journal={International journal of immunopharmacology},
  year={2000},
  volume={22 12},
  pages={1103-11}
}
The bacterial extract OM-89 (Uro-Vaxom) consisting of immunostimulating components derived from 18 Escherichia coli strains is used for the treatment of recurrent urinary tract infections. We investigated in the mouse the immunogenicity of the bacterial extract after oral administration. After repeated administration of OM-89, a specific serum IgG and IgA response against a number of bacterial strains was obtained. Supernatants of cell cultures prepared from the urogenital tract of immunized… CONTINUE READING
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