Immunoregulatory properties of clinical grade mesenchymal stromal cells: evidence, uncertainties, and clinical application

@inproceedings{Mnard2013ImmunoregulatoryPO,
  title={Immunoregulatory properties of clinical grade mesenchymal stromal cells: evidence, uncertainties, and clinical application},
  author={C{\'e}dric M{\'e}nard and Karin Tarte},
  booktitle={Stem Cell Research & Therapy},
  year={2013}
}
Mesenchymal stromal cell (MSC)-based therapy holds great promise for treating immune disorders and for regenerative medicine in agreement with their paracrine trophic and immunosuppressive activities. Various processes have been developed worldwide to produce clinical grade MSCs but, so far, it is not known if one given MSC is more efficient than another. In addition, while their broad activity on innate and adaptative immune cell subsets is now widely admitted, the precise mechanisms… CONTINUE READING

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