Immunoregulatory lymphokines in rheumatoid joints. I. Search for interleukin 2 in synovial fluid.

@article{Egeland1987ImmunoregulatoryLI,
  title={Immunoregulatory lymphokines in rheumatoid joints. I. Search for interleukin 2 in synovial fluid.},
  author={Thore Egeland and Hans Lund},
  journal={Scandinavian journal of immunology},
  year={1987},
  volume={25 1},
  pages={101-6}
}
Since there have been conflicting findings about the presence of interleukin 2 (IL-2) in synovial fluid (SF) of patients with rheumatoid arthritis (RA), we decided to study this subject ourselves. In a sensitive assay utilizing CTLL-2 as indicator cells, no IL-2-like activity was found in SF from any of the 15 RA patients studied. Treatment of SF with hyaluronidase, dialysation, heating to 56 degrees C for 1 h, preincubation of CTLL-2 with SF prior to washing and incubation all resulted in no… CONTINUE READING

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