Immunoregulation of dendritic cells by the receptor T cell Ig and mucin protein-3 via Bruton's tyrosine kinase and c-Src.

Abstract

The receptor T cell Ig and mucin protein-3 (TIM-3) has emerged as an important regulator of innate immune responses. However, whether TIM-3-induced signaling promotes or inhibits the activation and maturation of dendritic cells (DCs) still remains uncertain. In addition, the TIM-3 signaling events involved in this immunoregulatory function are yet to be… (More)
DOI: 10.4049/jimmunol.1400395

Topics

Cite this paper

@article{Maurya2014ImmunoregulationOD, title={Immunoregulation of dendritic cells by the receptor T cell Ig and mucin protein-3 via Bruton's tyrosine kinase and c-Src.}, author={Neeraj Maurya and Ravindra K. Gujar and Mamta Gupta and Vinod Kumar Yadav and Saurabh Verma and Pradip Sen}, journal={Journal of immunology}, year={2014}, volume={193 7}, pages={3417-25} }