Immunoreactivity and guanosine 3',5'-cyclic monophosphate activating actions of various molecular forms of human B-type natriuretic peptide.

@article{Heublein2007ImmunoreactivityAG,
  title={Immunoreactivity and guanosine 3',5'-cyclic monophosphate activating actions of various molecular forms of human B-type natriuretic peptide.},
  author={Denise M. Heublein and Brenda K. Huntley and Guido Boerrigter and Alessandro Cataliotti and Sharon M. Sandberg and Margaret May Redfield and John C Jr. Burnett},
  journal={Hypertension},
  year={2007},
  volume={49 5},
  pages={
          1114-9
        }
}
Recent studies support the speculation that different molecular forms of the cardiac hormone BNP with differential biological activity may circulate in heart failure and be detected by conventional assays. In the current study we determined the ability of 3 widely used conventional assays to detect these different forms thought to circulate in heart failure. We also evaluated the ability of pro-BNP (1-108), N-terminal peptide (NT)-pro-BNP (1-76), and BNP 3-32, the latter a cleavage product of… CONTINUE READING

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Corin gene expression inversely related to increased BNP expression in advanced cardiomyopathy: Setting the stage for inefficient natriuretic peptide processing in heart failure. Circulation

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