Immunoreactive trypsin levels in neonates with meconium ileus

  title={Immunoreactive trypsin levels in neonates with meconium ileus},
  author={L. C. Steven and Gil Gavel and David Z. Young and Robert Carachi},
  journal={Pediatric Surgery International},
Serum immunoreactive trypsin (IRT) is used as a screening test for cystic fibrosis (CF) in neonates in many countries. Variations in IRT levels are observed in healthy and cystic neonates within the first few weeks of life. Fifteen percentage of CF neonates present with meconium ileus (MI). We hypothesised that there may be differences in serum IRT levels in cystic babies with simple and complicated MI. The aim of this study was to investigate the serum levels of IRT in neonates with CF… CONTINUE READING