Immunoradiometric assay of insulin, intact proinsulin and 32–33 split proinsulin and radioimmunoassay of insulin in diet-treated Type 2 (non-insulin-dependent) diabetic subjects

@article{Clark1992ImmunoradiometricAO,
  title={Immunoradiometric assay of insulin, intact proinsulin and 32–33 split proinsulin and radioimmunoassay of insulin in diet-treated Type 2 (non-insulin-dependent) diabetic subjects},
  author={Penelope M.S. Clark and Jonathan C Levy and L. Cox and M. Dallas Burnett and Robert C. Turner and Charles Nicholas Hales},
  journal={Diabetologia},
  year={1992},
  volume={35},
  pages={469-474}
}
SummaryPlasma insulin, intact proinsulin and 32–33 split proinsulin measured by specific immunoradiometric assays and insulin and C-peptide measured by radioimmunoassay were measured during a constant infusion of glucose test in ten diet-treated subjects with a history of Type 2 (non-insulin-dependent) diabetes (termed diabetic subjects), mean fasting plasma glucose 6.0 ± 1.0 mmol/l (mean ± SD), and 12 non-diabetic control subjects. Immunoreactive insulin concentrations measured by… CONTINUE READING

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Proinsulin processing in the diabetic Goto-Kakizaki rat.

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