Immunoprophylaxis to prevent mother-to-child transmission of HIV-1.


Antiretroviral therapy can profoundly reduce the risk of mother-to-child transmission (MTCT) of HIV, but the drugs have a relatively short half-life and should thus be administered throughout breast-feeding to optimally prevent postnatal infection of the infant. The potential toxicities and the development of resistance may limit the long-term efficacy of… (More)


Cite this paper

@article{Safrit2004ImmunoprophylaxisTP, title={Immunoprophylaxis to prevent mother-to-child transmission of HIV-1.}, author={Jeffrey T. Safrit and Ruth M. Ruprecht and Flavia Ferrantelli and Weidong Xu and Moiz Kitabwalla and Koen K A Van Rompay and Marta L Marthas and Nancy L Haigwood and John R. Mascola and Katherine F Luzuriaga and Samuel A. Jones and Bonnie J. Mathieson and Marie-Louise Newell}, journal={Journal of acquired immune deficiency syndromes}, year={2004}, volume={35 2}, pages={169-77} }