Immunophenotyping of Plasma Cells

@article{Rawstron2006ImmunophenotypingOP,
  title={Immunophenotyping of Plasma Cells},
  author={A. Rawstron},
  journal={Current Protocols in Cytometry},
  year={2006},
  volume={36}
}
  • A. Rawstron
  • Published 2006
  • Medicine
  • Current Protocols in Cytometry
Plasma cell enumeration and immunophenotyping has been shown to be of value in predicting the outcome for patients with myeloma. Detection of abnormal plasma cells at a leukocyte level >0.01% at the end of therapy predicts early relapse. Although clonally related populations at varying stages of differentiation are reported to be present in myeloma, only the CD138+ fraction has been shown to directly correlate with the outcome. In addition, the plasma cell immunophenotype in monoclonal… Expand
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