Immunophenotyping analysis in invasive micropapillary carcinoma of the breast: role of CD24 and CD44 isoforms expression.

@article{Simonetti2012ImmunophenotypingAI,
  title={Immunophenotyping analysis in invasive micropapillary carcinoma of the breast: role of CD24 and CD44 isoforms expression.},
  author={Sara Simonetti and Luigi Maria Terracciano and Inti Zlobec and Ergin Kilic and Loredana Stasio and Maria Quarto and Guido Pettinato and Luigi Insabato},
  journal={Breast},
  year={2012},
  volume={21 2},
  pages={165-70}
}
We analyzed immunohistochemically the expression of CD24 and spliced variants of CD44v5 and v9 in invasive micropapillary carcinoma (IMPC) of the breast that is a rather aggressive tumor characterized by alteration of cells adhesion molecules, early lymph node metastases and poor prognosis. We analyzed 31 high-grade IMPCs and compared their expression to 22 high grade (G3) invasive ductal carcinomas of the breast (IDCs). We found a higher expression of CD24 in high-grade IMPCs with a peculiar… CONTINUE READING