Immunophenotypic predictive profiling of BRCA1-associated breast cancer

Abstract

The immunophenotypic predictive profile of BRCA1-associated cancers including major predictive markers, i.e., PARP-1, EGFR, c-kit, HER-2, and steroid hormones (ER/PR) that may have therapeutic relevance has not yet been reported in a comprehensive study. Using immunohistochemistry, we examined the expression of these proteins in a large cohort of BRCA1… (More)
DOI: 10.1007/s00428-010-0988-3

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