Immunophenotypic Lymphocyte Profiles in Human African Trypanosomiasis

  title={Immunophenotypic Lymphocyte Profiles in Human African Trypanosomiasis},
  author={Caroline Boda and Bertrand Courtioux and Pierre Roques and Lynda Pervieux and G{\'e}d{\'e}on Vatunga and Th{\'e}ophile Jos{\'e}nando and Constant Roger Ayenengoye and Bernard Bouteille and Marie-Odile Jauberteau and Sylvie Bisser},
  booktitle={PloS one},
Human African trypanosomiasis (HAT) is a deadly vector-born disease caused by an extracellular parasite, the trypanosome. Little is known about the cellular immune responses elicited by this parasite in humans. We used multiparameter flow cytometry to characterize leukocyte immunophenotypes in the blood and cerebrospinal fluid (CSF) of 33 HAT patients and 27 healthy controls identified during a screening campaign in Angola and Gabon. We evaluated the subsets and activation markers of B and T… CONTINUE READING