Immunophenotypic, cytogenetic, and mutational characterization of cell lines derived from myelodysplastic syndrome patients after progression to acute myeloid leukemia.

@article{Palau2017ImmunophenotypicCA,
  title={Immunophenotypic, cytogenetic, and mutational characterization of cell lines derived from myelodysplastic syndrome patients after progression to acute myeloid leukemia.},
  author={Anna Palau and Mar Mallo and Laura Palomo and In{\'e}s Rodr{\'i}guez-Hern{\'a}ndez and Jeannine Diesch and Diana Carolina Dur{\'a}n Campos and Isabel Patricia Granada and Jordi Bombard{\'o} Junc{\'a} and Hans Guenter Drexler and Francesc Sol{\'e} and Marcus Buschbeck},
  journal={Genes, chromosomes & cancer},
  year={2017},
  volume={56 3},
  pages={
          243-252
        }
}
Leukemia cell lines have been widely used in the hematology field to unravel mechanistic insights and to test new therapeutic strategies. Myelodysplastic syndromes (MDS) comprise a heterogeneous group of diseases that are characterized by ineffective hematopoiesis and frequent progress to acute myeloid leukemia (AML). A few cell lines have been established from MDS patients after progression to AML but their characterization is incomplete. Here we provide a detailed description of the… CONTINUE READING
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