Immunopharmacology of CpG oligodeoxynucleotides and ribavirin.

@article{Vollmer2004ImmunopharmacologyOC,
  title={Immunopharmacology of CpG oligodeoxynucleotides and ribavirin.},
  author={Joerg Vollmer and Robert A. Rankin and Hanna Hartmann and Marion Jurk and Ulrike Samulowitz and Tanja Wader and Andrea Janosch and Christian Schetter and Arthur M. Krieg},
  journal={Antimicrobial agents and chemotherapy},
  year={2004},
  volume={48 6},
  pages={2314-7}
}
To investigate their potential mechanisms of action, the nucleoside analogue ribavirin and a TLR9 agonist were compared. The CpG oligodeoxynucleotides (ODN) demonstrated strong TLR9-related Th1-type effects, and ribavirin appeared only to mediate signaling in TLR-transfected cells. CpG ODN represent a promising new type of therapeutic drug for hepatitis C or other infectious diseases. 
14 Citations
15 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 15 references

Similar Papers

Loading similar papers…