• Corpus ID: 16818980

Immunoperoxidase Localization of Colonie Mucoprotein Antigen in Neoplastia Tissues1

@inproceedings{Gold1981ImmunoperoxidaseLO,
  title={Immunoperoxidase Localization of Colonie Mucoprotein Antigen in Neoplastia Tissues1},
  author={David V. Gold},
  year={1981}
}
  • D. Gold
  • Published 1981
  • Medicine, Biology
The distribution of colonie mucoprotein antigen in various types of cancer was examined to determine whether the anti gen might have a role as a tissue marker. An antiserum pre pared against normal colon-derived colonie mucoprotein anti gen and appropriately absorbed with mucinous ovarian cystadenocarcinoma fluid had reactivity limited to the colon and cecum when tested by immunoperoxidase against various nor mal adult tissue specimens. Among colon carcinomas, 60% of the tumors were stained… 

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This analysis demonstrated the existence of a family of mucoproteins with a common gastrointestinal specific determinant(s), as seen by this antiserum, which showed a greater structural similarity than did mucobroteins from distant regions.
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