Immunopathology of psoriasis

@article{Jablonska1979ImmunopathologyOP,
  title={Immunopathology of psoriasis},
  author={Stephania Jablonska and Ernst H. Beutner and Walter L. Binder and Maria Jarząbek-Chorzelska and Genowefa Rzęsa and Olena Chowaniec},
  journal={Archives of Dermatological Research},
  year={1979},
  volume={264},
  pages={65-71}
}
Immunofluorescence (IF) studies by the direct and indirect methods demonstrate immunoglobulins and complement bound in vivo in psoriatic scales. The IF pattern is comparable to that of stratum corneum antibodies (SCAb) bound in vitro on specific substrate, as visualized by the indirect IF method. Formation of immune complexes can be responsible for the “squirting papilla” phenomenon, and conversion of the stratum corneum — which is normally an inaccessible antigen — into its reactive form seems… CONTINUE READING
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