Immunopathology and dexamethasone therapy in a new model for malaria-associated acute respiratory distress syndrome

@inproceedings{Steen2010ImmunopathologyAD,
  title={Immunopathology and dexamethasone therapy in a new model for malaria-associated acute respiratory distress syndrome},
  author={Philippe E. Van den Steen and Nathalie Geurts and Katrien Deroost and Ilse Van Aelst and Sebastien Verhenne and Hubertine Heremans and Jo Van Damme and Ghislain Opdenakker},
  booktitle={American journal of respiratory and critical care medicine},
  year={2010}
}
RATIONALE Malaria infection is often complicated by malaria-associated acute respiratory distress syndrome (MA-ARDS), characterized by pulmonary edema and hemorrhages. No efficient treatments are available for MA-ARDS and its pathogenesis remains poorly understood. OBJECTIVES Development of a new animal model for MA-ARDS to explore the pathogenesis and possible treatments. METHODS C57BL/6 mice were infected with Plasmodium berghei NK65, and the development of MA-ARDS was evaluated by the… CONTINUE READING