Immunopathogenesis of primary biliary cirrhosis: an old wives' tale

Abstract

Primary biliary cirrhosis (PBC) is a cholestatic liver disease characterised by the autoimmune destruction of the small intrahepatic bile ducts. The disease has an unpredictable clinical course, but may progress to fibrosis and cirrhosis. Although medical treatment with urseodeoxycholic acid is largely successful, some patients may progress to liver failure… (More)
DOI: 10.1186/1742-4933-8-12

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