Immunopathogenesis of HIV infection.

  title={Immunopathogenesis of HIV infection.},
  author={Ramesh Shivram Paranjape},
  journal={The Indian journal of medical research},
  volume={121 4},
Progression of HIV infection is largely dependent on the interaction between the viral factors and host factors. HIV primarily infects the CD4 lymphocytes in the body. It brings about the destruction of CD4 cells through multiple mechanisms including apoptosis. The loss of CD4 cell population ultimately leads to the inability of infected person to deal with opportunistic organisms. Host genetic factors such as HLA polymorphism and HIV co-receptor polymorphism may influence either susceptibility… CONTINUE READING

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