Immunomodulatory effects of aqueous extract of Ocimum basilicum (Linn.) and some of its constituents on human immune cells

@inproceedings{Tsai2011ImmunomodulatoryEO,
  title={Immunomodulatory effects of aqueous extract of Ocimum basilicum (Linn.) and some of its constituents on human immune cells},
  author={Kuen-daw Tsai and Been Ren Lin and Daw-Shyong Perng and James Cheng-Chung Wei and Yang Wen Yu and J. Albert Cherng},
  year={2011}
}
Ocimum basilicum Linn. (OB) is an edible plant with high concentrations of caffeic (CA) and p-coumaric acid (pCA). In this study, the authors evaluated the immunomodulatory activities of aqueous extract of OB, CA and pCA on human peripheral blood mononuclear cells (PBMC) by lymphoproliferation test, and defined the responding cells by flow cytometry, secretion of various cytokines by ELISA, and expression of mRNA by quantitative Real Time-PCR (qPCR) methods. At concentrations tested (0.135, 0… CONTINUE READING

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