Immunomodulatory activity of recombinant α-gliadin conjugated to cholera toxin in DQ8 transgenic mice.

Abstract

Coeliac disease (CD) is characterized by an intestinal lesion sustained by an abnormal mucosal T-cell response to wheat gliadin. An immunological approach that is able to suppress this immune response is a perspective worth pursuing. Several strategies of antigen administration have been aimed at the downregulation of pathogenic T-cells. In particular, we… (More)
DOI: 10.1016/j.imlet.2017.05.004

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