• Corpus ID: 43056840

Immunomodulatory activity of methanolic leaf extract of Moringa oleifera in animals.

@article{Sudha2010ImmunomodulatoryAO,
  title={Immunomodulatory activity of methanolic leaf extract of Moringa oleifera in animals.},
  author={P. N. Sudha and Syed Mohammed Basheeruddin Asdaq and Sunil S Dhamingi and Gowda Kallenahalli Chandrakala},
  journal={Indian journal of physiology and pharmacology},
  year={2010},
  volume={54 2},
  pages={
          133-40
        }
}
AIM The aim of the present study was to investigate the immunomodulatory action of methanolic extract of Moringa oleifera (MEMO) in an experimental model of immunity. The cellular immunity was evaluated using neutrophil adhesion test, cyclophosphamide induced neutropenia and carbon clearance assay, whereas, humoral immunity was tested by mice lethality test, serum immunoglobulin estimation and indirect haemagglutination assay in animals. Administration of MEMO (250 and 750 mg/kg, po) and Ocimum… 

Tables from this paper

EVALUATION OF IMMUNOMODULATORY ACTIVITY OF PETROLEUM ETHER EXTRACT OF SEEDS OF PITHECELLOBIUM DULCE IN WISTAR RATS
TLDR
The data showed that PEPD possesses potential for augmenting immune activity by cellular and humoral mediated mechanisms and also significantly restores the biochemical and histopathological parameters.
Immunomodulatory activity of methanolic leaf extract of Moringa oleifera in Wistar albino rats
TLDR
Moringa oleifera methanolic leaf extract caused a significant immunostimulatory effect on both the cell-mediated and humoral immune systems in the Wistar albino rats.
Immunomodulatory Activity of Terminalia Bellirica Extract in MICE
TLDR
The study demonstrated that T. bellirica triggers both non-specific and specific cellular immunity in mice, and shows significant protection against cyclophosphamide induced neutropenia.
IMMUNOSTIMULATORY EFFECT OF METHANOLIC LEAVES EXTRACT OF PSIDIUM GUAJAVA ( GUAVA ) ON HUMORAL AND CELL-MEDIATED IMMUNITY IN MICE
TLDR
It is suggested that Guava leaves extract can stimulate both humoral and cellmediated immunity in mice.
Immunomodulatory effect of Moringa peregrina leaves, ex vivo and in vivo study
This study was conducted to assess the in vivo and ex vivo immunomodulatory effect of the ethanol leaves extract of Moringa peregrina in Balb/c mice. For this study, five groups of 5 Balb/c mice were
Palliative effects of Moringa olifera ethanolic extract on hemato-immunologic impacts of melamine in rats.
Evaluation of Immunomodulatory activity of Diosgenin in rats
TLDR
The study indicates that Diosgenin triggers stimulatory effect on specific and nonspecific immune response, which could be attributed due to its saponin glycoside.
The Potency of Nanoparticle of Pinus merkusii as Immunostimulatory on Male Wistar Albino Rat
TLDR
It can be concluded that nanoparticle extract of P. merkusii possesses immunostimulatory activity and has therapeutic potential for the prevention of immune-depressed conditions.
Immunomodulatory effects of Moringa oleifera leaves aqueous extract in sheep naturally co-infected with Fasciola gigantica and Clostridium novyi
TLDR
Evaluating the in vivo fasciolicidal activity of Moringa (M.) oleifera leaf aqueous extract oral administration as well as its antibacterial activity against Clostridium (C.) novyi in sheep naturally co-infected with fAscioliasis showed that treatment with M. olifera improved the body weight gain and decreased fecal egg count in lightly and heavily infected groups compared to the nontreated group.
Some newer marker phytoconstituents in methanolic extract of Moringa oleifera leaves and evaluation of its immunomodulatory and splenocytes proliferation potential in rats
TLDR
GC-MS study revealed four new compounds in MOLE apart from promising its immunomodulatory potential based on humoral immune response, percentage increase in T-lymphocytes count, and induction of splenocytes proliferation.
...
...

References

SHOWING 1-10 OF 57 REFERENCES
Preliminary immunomodulatory activities of methanol extracts of Eclipta alba and Centella asiatica.
TLDR
Regression analysis showed linearity in patterns of the dose-response relationship, greatest in the case of the phagocytic index, moderate in the WBC count and lowest in the antibody titer.
Inhibitory Action of Ethanolic Extract of Seeds of Moringa oleifera Lam. On Systemic and Local Anaphylaxis
TLDR
A potential role for MOEE as a source of anti-anaphylactic agents for use in allergic disorders is suggested.
Hepatoprotective activity of Moringa oleifera on antitubercular drug-induced liver damage in rats.
TLDR
Results of this study showed that treatment with M. oleifera extracts or silymarin appears to enhance the recovery from hepatic damage induced by antitubercular drugs.
Study of the immunomodulatory activity of Haridradi ghrita in rats
TLDR
HG significantly potentiated the cellular immunity by facilitating the footpad thickness response to sheep RBCs in sensitized rats and shows preferential stimulation of the components of cell-mediated immunity.
Hypotensive constituents from the pods of Moringa oleifera.
TLDR
Two new compounds, O-[2'-hydroxy-3'-(2"-heptenyloxy)]-propyl undecanoate and O-ethyl-4-[(alpha-L-rhamnosyloxy)-benzyl] carbamate along with the known substances methyl p-hydroxybenzoate and beta-sitosterol have also been isolated and showed promising hypotensive activity.
...
...