• Corpus ID: 42190469

Immunomodulatory activity of aqueous extract of Ocimum sanctum in rat

@inproceedings{Jeba2011ImmunomodulatoryAO,
  title={Immunomodulatory activity of aqueous extract of Ocimum sanctum in rat},
  author={R. Caroline Jeba and Rama Vaidyanathan},
  year={2011}
}
Background: Biochemical, haematological and Immunomodulatory effect of Ocimum sanctum in rat was studied. Objective: To evaluate the immunomodulatory effect of Ocimum sanctum in rat Methods: Aqueous extract of Ocimum sanctum were administered oraly at doses of 100, 200 mg/kg/day for 45 days in wistar albino rats. Immunomodulatory effect and biochemical and haematological changes were tested by standard methods. Results: Aqueous extract of the Ocimum sanctum showed increasing antibody production… 
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O. basilicum showed immunomodulatory effect in wister albino rat that enhanced the antibody titre value and improves the RBC and haemoglobin count.
Effect of Ocimum Sanctum (Tulsi) on Serum Calcium And Serum Inorganic Phosphate Activities of Male Albino Rat
TLDR
Investigation of the effect of different schedules of oral administration of tulsi( Ocimum sanctum)leaf on serum calcium and serum phosphate activities of male albino rats found significant changes were observed in serumcium and serum inorganic phosphate activities.
Review on Pharmacological Potential of Ocimum sanctum L.
TLDR
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It is appropriate to conclude that the plant extract of Ocimum sanctum may act as a potent Immunostimulant in Clarias batrachus Linn.
TOXICOLOGICAL EVAL UATION OF THE AQUEOUS LEAF EXTRACT OF OCIMUM GRATISSIMUM IN WISTAR RATS
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It was concluded that ethnomedicinal application of Ocimum gratissimum is quite safe at lower doses but it is hepatotoxi c and nephrotoxic at higher doses.
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TLDR
Overall, administration of the extracts of these two plants in combination as compared to their administration alone rescued the affected mice from the disease greatly, which can be attributed to their antileishmanial and immunomodulatory activities.
Effect of Hydroalcoholic Extract of Artemisia dracunculus L. (Tarragon) on the Levels of Serum Proteins in Small Laboratory Mice
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The effect of hydroalcoholic extract of tarragon on the levels of serum proteins in mice was determined to determine the role of blood plasma proteins in maintaining the body homeostasis.
ANTIPSYCHOTIC POTENTIALS OF OCIMUM SANCTUM LEAVES
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The results suggest that OCLP posse’s antipsychotic activity can be explored to explore the mechanism of action of the plant drug with respect to anti-dopaminergic functions and help to establish the plant as an antipsychotics agent.
ETHNOMEDICOBOTANICAL STUDY ON OCIMUM SANCTUM L. (TULSI) - A REVIEW
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The effects of O. sanctum may delay the development some life threating complications and this work stimulates the researchers for further research on the potential use of this medicinal plants having pharmaceutical potential.
Therapeutic activities of Ocimum tenuiflorum accounted in last decade: a review.
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The review accounts for anthelmintic, antiaflatoxigenic, antibacterial, anticancer, antidepressant, antidiabetic, antifungal/anticandidal, antimetastatic, antimicrobial, antioxidant, antiprotozoal, antistress, antiviral, anxiety, cardio protective, chemoprotective, cognition improvement and wound healing activities.
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References

SHOWING 1-10 OF 26 REFERENCES
COMPARATIVE EVALUATION OF ALCOHOLIC AND AQUEOUS EXTRACTS OF OCIMUM SANCTUM FOR IMMUNOMODULATORY ACTIVITY
TLDR
The study shown stimulatory effect on the humoral and delayed type hypersensitivity but the alcoholic extract was more potent in producing immune stimulation than aqueous extract.
Ocimum sanctum--a preliminary study evaluating its immunoregulatory profile in albino rats.
Evaluation of immunomodulatory potential of Ocimum sanctum seed oil and its possible mechanism of action.
Immunomodulatory and antitumour activities of Tinospora cordifolia
Immunomodulatory effects of neem (Azadirachta indica) oil.
Therapeutic uses of Ocimum sanctum Linn (Tulsi) with a note on eugenol and its pharmacological actions: a short review.
TLDR
Eugenol (1-hydroxy-2-methoxy-4-allylbenzene), the active constituent present in Ocimum sanctum L., has been found to be largely responsible for the therapeutic potentials of Tulsi, and pharmacological studies have established a scientific basis for therapeutic uses of this plant.
Immunomodulatory and Anti-Tumour Polysaccharides from Medicinal Plants
TLDR
The purification, characterization and structural elucidation of immunomodulatory polysaccharides from medicinal plants may have important implications in the immunotherapy of cancer and in the treatment of various other diseases.
A review of the plants of the genus Phyllanthus: Their chemistry, pharmacology, and therapeutic potential
TLDR
Together this data strongly supports the view that the plants belonging to the genus Phyllanthus have potential beneficial therapeutic actions in the management of hepatitis B, nefrolitiase, and in painful disorders.
Shosaiko-to and other Kampo (Japanese herbal) medicines: a review of their immunomodulatory activities.
Antifungal effects of different plant extracts and their major components of selected Aloe species
Different extracts of both fresh and dry leaves of Aloe eru A. Berger, A. vera L. Webb & Berth and A. arborescens Mill. were screened for their antifungal activity against Aspergillus niger,…
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