Immunomodulation of liver injury by Ascaris suum extract in an experimental model of autoimmune hepatitis

Abstract

Adult worm extract from Ascaris suum (Asc) has immunosuppressive activity and elicits Th2/IL-4/IL-10 response. This study evaluated the prophylactic and therapeutic effect of Asc in a murine model of concanavalin A (ConA)-induced autoimmune hepatitis (AIH). BALB/c mice received ConA, iv, (20 mg/kg), and three groups of animals were formed: (1) AIH, received… (More)
DOI: 10.1007/s00436-014-3994-6

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