Immunomodulation of human natural killer cell cytotoxic function by organochlorine pesticides.

@article{Reed2004ImmunomodulationOH,
  title={Immunomodulation of human natural killer cell cytotoxic function by organochlorine pesticides.},
  author={Adrian Reed and Leticia Dzon and Bommanna G Loganathan and Margaret M Whalen},
  journal={Human & experimental toxicology},
  year={2004},
  volume={23 10},
  pages={463-71}
}
Organochlorine pesticides are used worldwide. To our knowledge there have been no studies dealing with the effects of these agents under in vitro conditions on human natural killer (NK) cell cytotoxic function. NK cells play a central role in immune defense against tumor development and viral infections. Thus, any agent that interferes with the ability of NK cells to lyse their targets could increase the risk of tumor incidence and/or viral infections. In this study, we examined the effects of… CONTINUE READING
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