Immunomodulation of Fungal β-Glucan in Host Defense Signaling by Dectin-1

  title={Immunomodulation of Fungal $\beta$-Glucan in Host Defense Signaling by Dectin-1},
  author={Sainkhuu Batbayar and Dong Hee Lee and Ha Won Kim},
  journal={Biomolecules \& Therapeutics},
  pages={433 - 445}
During the course of evolution, animals encountered the harmful effects of fungi, which are strong pathogens. Therefore, they have developed powerful mechanisms to protect themselves against these fungal invaders. β-Glucans are glucose polymers of a linear β(1,3)-glucan backbone with β(1,6)-linked side chains. The immunostimulatory and antitumor activities of β-glucans have been reported; however, their mechanisms have only begun to be elucidated. Fungal and particulate β-glucans, despite their… 

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