Immunomodulation of Fungal β-Glucan in Host Defense Signaling by Dectin-1
@article{Batbayar2012ImmunomodulationOF, title={Immunomodulation of Fungal $\beta$-Glucan in Host Defense Signaling by Dectin-1}, author={Sainkhuu Batbayar and Dong Hee Lee and Ha Won Kim}, journal={Biomolecules \& Therapeutics}, year={2012}, volume={20}, pages={433 - 445} }
During the course of evolution, animals encountered the harmful effects of fungi, which are strong pathogens. Therefore, they have developed powerful mechanisms to protect themselves against these fungal invaders. β-Glucans are glucose polymers of a linear β(1,3)-glucan backbone with β(1,6)-linked side chains. The immunostimulatory and antitumor activities of β-glucans have been reported; however, their mechanisms have only begun to be elucidated. Fungal and particulate β-glucans, despite their…
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