Immunomodulation in the treatment of endometriosis-associated subfertility: use of pentoxifylline to reverse the inhibition of fertilization by surgically induced endometriosis in a rodent model.

@article{Steinleitner1991ImmunomodulationIT,
  title={Immunomodulation in the treatment of endometriosis-associated subfertility: use of pentoxifylline to reverse the inhibition of fertilization by surgically induced endometriosis in a rodent model.},
  author={Alex Steinleitner and H. R. Lambert and M T Suarez and Narayana Pauline Serpa and Sandip Roy},
  journal={Fertility and sterility},
  year={1991},
  volume={56 5},
  pages={975-9}
}
OBJECTIVE To determine the effect of pentoxifylline on early reproductive performance in an animal model for endometriosis. DESIGN Preclinical blinded study in a rodent model. SETTING Animal research laboratory. PARTICIPANTS Sexually mature female golden hamsters. INTERVENTIONS At laparotomy, groups of hamsters were subjected to: (1) excision of the right uterine horn and (2) excision of the right uterine horn with explantation of four 2-cm2 uterine fragments onto the left uterine… CONTINUE READING
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