Immunomodulating effects of α-interferon inPseudomonas aeruginosa infection

Abstract

It is shown thatPseudomonas aeruginosa infection is accompanied in mice by impaired functional activity of lymphocytes and by greatly increased production of the mediators interleukin-1 and tumor necrosis factor, which prevents the development of adequate cellmediated immune reactions and inhibits effector functions of macrophages and killer cells. After a… (More)
DOI: 10.1007/BF02445140

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