Immunometabolism: Physiologic role of IL-1β in glucose homeostasis


Immunology shows that elevated glucose levels after feeding induce macrophages to secrete IL‐1β, which in turn promotes postprandial insu‐ lin secretion. As insulin enhances macrophage production of IL‐1β, the findings might explain why insulin treatment can result in insulin resist‐ ance. The findings also support the use of therapeutic strategies in type… (More)
DOI: 10.1038/nrendo.2017.11


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.